Jaundice is a highly prevalent condition.

9 million babies are born in the US and Europe each year.1 60-80% of these babies will develop jaundice.2,3

  • In many babies, this is a normal condition that can be easily treated.
  • Babies with both HYPERBILIRUBINEMIA and HEMOLYSIS are at greatest risk for adverse neurodevelopmental outcomes.4
  • According to the AAP Guidelines, newborns with a hemolytic condition need to receive phototherapy at lower levels of bilirubin than other newborns.5





Since 2004, the American Academy of Pediatrics has recommended the use of ETCO testing.

AAP Guidelines recommend the use of ETCO testing in newborns 35 weeks’ gestation or more who:5

  1. are receiving phototherapy, or
  2. have TSB rising rapidly, or
  3. have TSB approaching transfusion levels, or
  4. have jaundice unexplained by history and physical.


Published data show that ETCO testing, unlike blood tests, provides an accurate measure of hemolysis.6 The American Academy of Pediatrics (AAP) has recommended the use of ETCO to directly measure bilirubin production rates in newborns.5 Multiple clinical trials have validated the ability of the CoSense ETCO Monitor to measure ETCO, which may be used to detect the rate of hemolysis in newborns.7,8